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Among patients undergoing cardiac surgery, women are less likely than men to develop postoperative atrial fibrillation AF after adjustment for other relevant factors, but long-term mortality is higher for those women who do, according to a new analysis. Wagner led a recent study that identified a lower rate of guideline-recommended concomitant procedures to treat existing AF among women compared with men undergoing nonmitral cardiac surgeries. Sex-Based Interaction.
For the analysis, published online today in JAMA Network Open , Karamnov and colleagues looked at data from 21, patients mean age A slightly higher proportion of women compared with men developed postoperative AF The incidence of postoperative AF increased the risk of death for both men HR 1.
There was no such gap in mortality risk among men and women who did not develop postoperative AF. Karamnov argued that the data provide more confirmatory evidence that postoperative AF is not a benign condition, as previously thought. The findings also support further sex-based research into outcomes after cardiac surgery, he said.
Wagner agreed. But the findings also have implications for male patients, who are at an increased risk for mortality if they develop postoperative AF, she pointed out. But really, this is just the beginning for us to understand how we can truly optimize patient care after cardiac surgery.