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October 2, at am. Updated October 2, at pm. Two scientists who laid the groundwork for what would become among the most influential vaccines of all time have been awarded the Nobel Prize in medicine or physiology. Her remarks came on October 2 after a news briefing to announce the winners. As of September , more than In the year after their introduction, the shots are estimated to have saved nearly 20 million lives globally.

Chan School of Public Health in Boston. The mRNA vaccines work a bit differently than traditional immunizations. Most traditional vaccines use viruses or bacteria — either weakened or killed — or proteins from those pathogens to provoke the immune system into making protective antibodies and other defenses against future infections.

When a person gets an mRNA shot, the genetic material gets into their cells and triggers the cells to produce the viral protein for a short amount of time.

When the immune system sees the viral protein, it builds defenses to prevent serious illness if the person later gets infected with the coronavirus. In addition to protecting people from the coronavirus, mRNA vaccines may also work against other infectious diseases and cancer. Scientists might also use the technology to help people with certain rare genetic diseases make enzymes or other proteins they lack.